Is a protein whose key biological function is to regulate the colloidal osmotic pressure of blood. Widely used in various studies and applications. Made up of 583 amino acids, is a water-soluble protein with a calculated molecular weight of 66,430 Da. Six a-helices form three homologous domains of BSA. Depending on pH, it undergoes reversible conformational isomerization. The native structure of the protein becomes reactive and flexible on heating. Used for many applications, including the following: Used in cell culture, e.g. as a supplement in media prepared for culturing of oligodendrocytes. Used for the dilution of primary antibody solution in immunohistochemistry procedures. Used as a standard in the Bradford method of protein quantification. Used in blocking and permeabilization buffer for immunofluorescence studies.