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Suitability
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acts as a beta-lactamase resistant antibiotic, used
as an effective antibacterial against gram-negative bacteria, with the
notable exception of pseudomonas and penicillin-resistant strains of
streptococcus pneumoniae, used to treat infections of the bones, joints,
skin, respiratory tract and blood stream, used to study the effect of
expression, binding and inhibition of penicillin-binding proteins especially
PBP2 on bacterial cell wall mucopeptide synthesis, used to find new residues involved in cefotaxime
hydrolysis in CTX-M ß-lactamases, to study antibiotic-susceptible and
-resistant Streptococcus pneumoniae infections, and to study pneumococcal
pneumonia and the pharmokinetics of various treatments. MANUAL REVIEW REQUIRED.
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