Adenine, cytosine, thymine and guanine are the four main nucleobases found in nucleic acids DNA and RNA. Guanine is a purine derivative. It is reported to assemble into square-planar groups that resemble macrocycles, in which the bases interact via hydrogen bonds. In DNA and RNA, stretches of guanine bases are reported to form stable four stranded helices in the presence of sodium or potassium ions. The electrochemical oxidation of guanine has been studied in aqueous media at various carbon electrodes. It reacts with peroxynitrite under physiological conditions to afford 8-nitroguanine. Employed as a nucleobase incorporated into biological nucleic acids, suitable reagent used to investigate the mechanism of electrochemical oxidation of guanine and adenine using a glassy carbon microelectrode and cyclic and differential pulse voltammetry, used in the preparation of mixed-sequence peptide nucleic acid (PNA) monomers.
Guanine; 2-Aminohypoxanthine; 2-Amino-6-hydroxypurine; 2-Amino-1,7-dihydro-6H-purin-6-one; Guanin; Pearl essence; Natural White 1; 2-Amino-6-purinol; 6-Hydroxy-2-aminopurine; 2-Amino-1,9-dihydro-6H-purin-6-one; C.I. 75170; 2-Amino-9H-purin-6-ol; 2-Amino-3H-purin-6(7H)-one; 2-Amino-6-hydroxy-1H-purine; 2-Amino-1,9-dihydropurin-6-one; 2-Amino-1,9-dihydro-purin-6-one; 2-Amino-6,7-dihydro-3H-purin-6-one; GUA; 2-Aminohydropurin-6-one; GUN; 2-Amino-6-hydroxypurin; 2-Amino-1,7-dihydropurin-6-one; 2-Amino-6-oxypurin; 2-Amino-7H-purin-6-ol; Empirical Formula (Hill Notation): C5H5N5O; CAS Number: 73-40-5; Molecular Weight: 151.13; Beilstein/REAXYS Number: 9680; EC Number: 200-799-8; MDL number: MFCD00071533;
