Is commonly used for the conversion of carboxylic acid into the corresponding N-hydroxysuccinimidyl (NHS) ester. Used in the synthesis of N-succinimidyl 4-[18F]fluorobenzoate ([18F]SFB), a 18F-labeled agent used for labeling biomarkers. May also be used for the activation of carboxylic group of C16-chained alkanethiols that are used in developing surface plasmon resonance (SPR) sensors. Reactant for linking sensor molecules with amino groups to amino functionalized AFM tips, Reactant for synthesis of a polymer supported oranotin reagent for prosthetic group labeling of biological macromolecules with radioiodinem L-Rhamnose antigen, fluorinated rhodamines for optical microscopy and nanoscopy, c(RGDyK) targeted SN38 prodrug, and polyelectrolytes for thin film construction.