tBuXPhos, Certified® Reagent

tBuXPhos, Certified® Reagent

for analytical applications, synthesis, research, and development

Material has not been tested for animal or human or diagnostic or therapeutic use

Certificate of Analysis and Safety Data Sheets available upon request

Catalog Number

T11618717R

Package

HDPE or Amber Glass Bottle

CAS Number

564483-19-8

 Formula

C29H145P

Mw

424.64

Certificate of Analysis

Appearance: white powder; Assay: (HPLC) 98%; Elemental analysis (carbon) 81.16%; Identification: (FTIR spectra or Proton NMR spectra or Phosphorus NMR spectra) conforms to structure; Retest: 04/28;

Suitability

Is an air-stable, electron-rich biaryl phosphine ligand developed by the Buchwald group to enhance the reactivity of palladium catalysis during cross-coupling reactions, used in the preparation of [tBuXPhosAu(MeCN)]BAr4F, a gold catalyst for the intermolecular [2+2] cycloaddition of terminal arylalkynes with substituted alkenes to form functionalized cyclobutenes with high regioselectivity, is a ligand for Pd-catalyzed C-O and C-N bond formation, used in the following reactions: Palladium-catalyzed Tsuji-Trost substitution and cross-coupling of benzylic fluorides, Palladium-catalyzed C-N cross-coupling of sulfinamides and aryl halides, Palladium-catalyzed rapid methoxylation and deuteriomethoxylation of bromo-chalcones.